Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50389007 (CHEMBL1214255 | US9321743, SD41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.96E+3 | n/a | n/a | n/a | n/a | 5.0 | 37 |
The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” US Patent | Assay Description Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain... | US Patent US9321743 (2016) BindingDB Entry DOI: 10.7270/Q26D5RVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50389007 (CHEMBL1214255 | US9321743, SD41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of rat recombinant NAAA expressed in HEK293 cells after 30 mins | J Med Chem 53: 5770-81 (2010) Article DOI: 10.1021/jm100582w BindingDB Entry DOI: 10.7270/Q2X0689M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50389007 (CHEMBL1214255 | US9321743, SD41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino Carlo Bo Curated by ChEMBL | Assay Description Inhibition of rat recombinant NAAA expressed in HEK293 cells using heptadecenoylethanolamide as substrate after 30 mins by LC/MS analysis | J Med Chem 55: 4824-36 (2012) Article DOI: 10.1021/jm300349j BindingDB Entry DOI: 10.7270/Q20P113N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50389007 (CHEMBL1214255 | US9321743, SD41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of rat NAAA | J Med Chem 63: 7475-7490 (2020) Article DOI: 10.1021/acs.jmedchem.0c00191 BindingDB Entry DOI: 10.7270/Q2V98CM4 | |||||||||||
More data for this Ligand-Target Pair |