BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'N-formyl peptide receptor 2' and Ligand = 'BDBM450350'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM450350
PNG
(US10676431, Example 113 | US11117861, Example 113)
Show SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O |r|
Show InChI InChI=1S/C26H25ClF3N4O3P/c1-26(2)13-34(24(35)22(26)33-25(36)32-18-9-7-14(27)12-17(18)28)19-10-8-15(20(29)21(19)30)16-6-5-11-31-23(16)38(3,4)37/h5-12,22H,13H2,1-4H3,(H2,32,33,36)/t22-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.390n/an/an/an/a


TBA

Assay Description
FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2ZK5KV9
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM450350
PNG
(US10676431, Example 113 | US11117861, Example 113)
Show SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O |r|
Show InChI InChI=1S/C26H25ClF3N4O3P/c1-26(2)13-34(24(35)22(26)33-25(36)32-18-9-7-14(27)12-17(18)28)19-10-8-15(20(29)21(19)30)16-6-5-11-31-23(16)38(3,4)37/h5-12,22H,13H2,1-4H3,(H2,32,33,36)/t22-/m0/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.390n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...


US Patent US10676431 (2020)


BindingDB Entry DOI: 10.7270/Q2N58QFS
More data for this
Ligand-Target Pair