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SMILES: CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O

InChI Key: InChIKey=JOOVJTBMQARIMY-QFIPXVFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM450350 (US10676431, Example 113 | US11117861, Example 113) Show SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O |r| Show InChI InChI=1S/C26H25ClF3N4O3P/c1-26(2)13-34(24(35)22(26)33-25(36)32-18-9-7-14(27)12-17(18)28)19-10-8-15(20(29)21(19)30)16-6-5-11-31-23(16)38(3,4)37/h5-12,22H,13H2,1-4H3,(H2,32,33,36)/t22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.390	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...				US Patent US10676431 (2020)
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM450350 (US10676431, Example 113 | US11117861, Example 113) Show SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O |r| Show InChI InChI=1S/C26H25ClF3N4O3P/c1-26(2)13-34(24(35)22(26)33-25(36)32-18-9-7-14(27)12-17(18)28)19-10-8-15(20(29)21(19)30)16-6-5-11-31-23(16)38(3,4)37/h5-12,22H,13H2,1-4H3,(H2,32,33,36)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM450350 (US10676431, Example 113 | US11117861, Example 113) Show SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O |r| Show InChI InChI=1S/C26H25ClF3N4O3P/c1-26(2)13-34(24(35)22(26)33-25(36)32-18-9-7-14(27)12-17(18)28)19-10-8-15(20(29)21(19)30)16-6-5-11-31-23(16)38(3,4)37/h5-12,22H,13H2,1-4H3,(H2,32,33,36)/t22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	0.390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM450350 (US10676431, Example 113 | US11117861, Example 113) Show SMILES CC1(C)CN(C(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1F)c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O |r| Show InChI InChI=1S/C26H25ClF3N4O3P/c1-26(2)13-34(24(35)22(26)33-25(36)32-18-9-7-14(27)12-17(18)28)19-10-8-15(20(29)21(19)30)16-6-5-11-31-23(16)38(3,4)37/h5-12,22H,13H2,1-4H3,(H2,32,33,36)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	590	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...				US Patent US10676431 (2020)
					More data for this Ligand-Target Pair