Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'N6-adenosine-methyltransferase catalytic subunit' and Ligand = 'BDBM50572910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572910 (CHEMBL4861007) Show SMILES Nc1ncnc2n(cc(-n3cccn3)c12)[C@@H]1O[C@H](COc2ccc3ccc(nc3c2)N2CCC2)[C@@H](O)[C@@H]1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572910 (CHEMBL4861007) Show SMILES Nc1ncnc2n(cc(-n3cccn3)c12)[C@@H]1O[C@H](COc2ccc3ccc(nc3c2)N2CCC2)[C@@H](O)[C@@H]1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
					More data for this Ligand-Target Pair