BindingDB PrimarySearch

Found 50 hits Enz. Inhib. hit(s) with Target = 'N6-adenosine-methyltransferase catalytic subunit'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586498 (CHEMBL5077332) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572906 (CHEMBL4854665) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572907 (CHEMBL4850503) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572908 (CHEMBL4872977) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572909 (CHEMBL4856985) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572910 (CHEMBL4861007) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572911 (CHEMBL4852677) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3 (unknown origin) using 3' biotinylated RNA (UCUGGACUAAA) and 3H-SAM as a substrate preincubated for 5 mins followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611058 (CHEMBL5279050) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611061 (CHEMBL5291234) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586497 (CHEMBL5076974) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586487 (CHEMBL5087497) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586500 (CHEMBL5078591) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586486 (CHEMBL5082067) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586499 (CHEMBL5092743) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586495 (CHEMBL5084119) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586494 (CHEMBL5092187) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586488 (CHEMBL5084812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586485 (CHEMBL5077723) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611058 (CHEMBL5279050) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586493 (CHEMBL5083998) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586489 (CHEMBL5094039) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50009672 (AdoHcy \| CHEMBL418052 \| S-(5'-adenosyl)-L-homocyst...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586483 (CHEMBL5091512) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586492 (CHEMBL5076504) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572911 (CHEMBL4852677) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572907 (CHEMBL4850503) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572909 (CHEMBL4856985) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572910 (CHEMBL4861007) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572908 (CHEMBL4872977) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50572906 (CHEMBL4854665) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00280 BindingDB Entry DOI: 10.7270/Q2GQ72JV
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586491 (CHEMBL5081806) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586490 (CHEMBL5083959) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586484 (CHEMBL5092569) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586496 (CHEMBL5072742) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586481 (CHEMBL5091996) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586480 (CHEMBL5094929) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586482 (CHEMBL5078612) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586479 (CHEMBL5081407) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611052 (CHEMBL5270921) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611059 (CHEMBL5286034) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611060 (CHEMBL5288865) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	5.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611055 (CHEMBL5282296) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PDB UniChem		n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611056 (CHEMBL5276433) Show SMILES CNC1CCC(O)(Cn2cnc3c(N)ncnc23)C(O)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611054 (CHEMBL5281978) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611057 (CHEMBL5286336) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611053 (CHEMBL5281651) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	3.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	4.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586498 (CHEMBL5077332) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Thermal stabilization of recombinant METTL3 (354 to 580 residues) (unknown origin) expressed in HEK293T cells assessed as non-aggregated METTL3-ePL p...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50611061 (CHEMBL5291234) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Homo sapiens)	BDBM50586498 (CHEMBL5077332) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	850	n/a	n/a	n/a	n/a
TBA					Assay Description Thermal stabilization of endogenously expressing full length METTL3 in human MOLM-13 cells assessed as stabilized METTL3 incubated for at 54 degC by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00773 BindingDB Entry DOI: 10.7270/Q2PK0M21
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)