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Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50326486'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))		BDBM50326486
PNG
(CHEMBL1243031 | N'-(3,4-dihydroxybenzylidene)-2-(3...)
Show SMILES Oc1ccc(C=NNC(=O)C(=O)c2cccc(c2)[N+]([O-])=O)cc1O |w:6.6|
Show InChI InChI=1S/C15H11N3O6/c19-12-5-4-9(6-13(12)20)8-16-17-15(22)14(21)10-2-1-3-11(7-10)18(23)24/h1-8,19-20H,(H,17,22)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.02E+3n/an/an/an/an/an/a



Vichem Chemie Research Ltd.

Curated by ChEMBL


Assay Description
Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay

J Med Chem 53: 6758-62 (2010)


Article DOI: 10.1021/jm1004368
BindingDB Entry DOI: 10.7270/Q2F18ZZ5
More data for this
Ligand-Target Pair