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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50190753'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM50190753
PNG
(2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(Cc2ccccc2)s1)C(O)=O
Show InChI InChI=1S/C21H27N3O3S/c1-2-8-16(18(25)26)14-21(11-6-7-12-21)19(27)22-20-24-23-17(28-20)13-15-9-4-3-5-10-15/h3-5,9-10,16H,2,6-8,11-14H2,1H3,(H,25,26)(H,22,24,27)
PDB

KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP

J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair