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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50403280'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM50403280
PNG
(CHEMBL65545)
Show SMILES OC(=O)[C@@H]1CCCN2CCC[C@H](NC(=O)[C@@H](S)Cc3ccccc3)C(=O)N12
Show InChI InChI=1S/C19H25N3O4S/c23-17(16(27)12-13-6-2-1-3-7-13)20-14-8-4-10-21-11-5-9-15(19(25)26)22(21)18(14)24/h1-3,6-7,14-16,27H,4-5,8-12H2,(H,20,23)(H,25,26)/t14-,15-,16-/m0/s1
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Similars
Article
n/an/a 3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against neutral endopeptidase (NEP) was determined

Bioorg Med Chem Lett 4: 2055-2060 (1994)


Article DOI: 10.1016/S0960-894X(01)80562-X
BindingDB Entry DOI: 10.7270/Q2PN96SK
More data for this
Ligand-Target Pair