Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM85434'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Rattus norvegicus (Rat))	BDBM85434 (NEP inhibitor, 6n) Show SMILES OC(=O)c1cc(NC(=O)C(CS)Cc2ccc(Cl)cc2)c[nH]1 Show InChI InChI=1S/C15H15ClN2O3S/c16-11-3-1-9(2-4-11)5-10(8-22)14(19)18-12-6-13(15(20)21)17-7-12/h1-4,6-7,10,17,22H,5,8H2,(H,18,19)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
R&D, Zambon Group Spa					Assay Description Enzyme inhibition assay using neutrol endopeptiase EC 3.4.24.11 (NEP).				J Enzym Inhib 12: 155-60 (1997) Article DOI: 10.3109/14756369709035816 BindingDB Entry DOI: 10.7270/Q2FQ9V4F
					More data for this Ligand-Target Pair