BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Neuraminidase' and Ligand = 'BDBM50068267'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuraminidase (Influenza A virus)	BDBM50068267 ((E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-ph...) Show SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant activity expressed in HEK293T cells after 2 hrs by spectrof...				Bioorg Med Chem Lett 21: 294-8 (2011) Article DOI: 10.1016/j.bmcl.2010.11.016 BindingDB Entry DOI: 10.7270/Q2N87DMZ
Chosun University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068267 ((E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-ph...) Show SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of wild type H1N1 swine influenza virus neuraminidase activity expressed in HEK293T cells after 2 hrs by spectrofluorometry				Bioorg Med Chem Lett 21: 294-8 (2011) Article DOI: 10.1016/j.bmcl.2010.11.016 BindingDB Entry DOI: 10.7270/Q2N87DMZ
Chosun University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068267 ((E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-ph...) Show SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of Influenza A H9N2 virus neuraminidase activity after 2 hrs by spectrofluorometry				Bioorg Med Chem Lett 21: 294-8 (2011) Article DOI: 10.1016/j.bmcl.2010.11.016 BindingDB Entry DOI: 10.7270/Q2N87DMZ
Chosun University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068267 ((E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-ph...) Show SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of Influenza A H1N1 virus neuraminidase activity after 2 hrs by spectrofluorometry				Bioorg Med Chem Lett 21: 294-8 (2011) Article DOI: 10.1016/j.bmcl.2010.11.016 BindingDB Entry DOI: 10.7270/Q2N87DMZ
Chosun University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM50068267 ((E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-ph...) Show SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Noncompetitive inhibition of Influenza A H1N1 virus neuraminidase activity by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 294-8 (2011) Article DOI: 10.1016/j.bmcl.2010.11.016 BindingDB Entry DOI: 10.7270/Q2N87DMZ
Chosun University Curated by ChEMBL					More data for this Ligand-Target Pair