Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-3/beta-2' and Ligand = 'BDBM50530216'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Homo sapiens (Human))	BDBM50530216 (CHEMBL4582201) Show SMILES [H][C@@]12CC[C@@]([H])(C1)[C@H]([C@@H]2N)c1ccc(Cl)nc1 |r,TLB:9:8:2.3:6,THB:10:7:2.3:6| Show InChI InChI=1S/C12H15ClN2/c13-10-4-3-9(6-15-10)11-7-1-2-8(5-7)12(11)14/h3-4,6-8,11-12H,1-2,5,14H2/t7-,8+,11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assay				J Med Chem 62: 1887-1901 (2019) Article DOI: 10.1021/acs.jmedchem.8b01372 BindingDB Entry DOI: 10.7270/Q2PR80F8
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Homo sapiens (Human))	BDBM50530216 (CHEMBL4582201) Show SMILES [H][C@@]12CC[C@@]([H])(C1)[C@H]([C@@H]2N)c1ccc(Cl)nc1 |r,TLB:9:8:2.3:6,THB:10:7:2.3:6| Show InChI InChI=1S/C12H15ClN2/c13-10-4-3-9(6-15-10)11-7-1-2-8(5-7)12(11)14/h3-4,6-8,11-12H,1-2,5,14H2/t7-,8+,11-,12+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assay				J Med Chem 62: 1887-1901 (2019) Article DOI: 10.1021/acs.jmedchem.8b01372 BindingDB Entry DOI: 10.7270/Q2PR80F8
					More data for this Ligand-Target Pair