Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50194315 ((2R,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01150 BindingDB Entry DOI: 10.7270/Q2K93C4G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50194315 ((2R,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Milano Pietro Pratesi Curated by ChEMBL | Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane | Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T | |||||||||||
More data for this Ligand-Target Pair |