Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50416398'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50416398 (CHEMBL1210643) Show SMILES O=C(Cc1nc(-c2ccc3OCOc3c2)c2ccccc2n1)NC1Cc2ccccc2C1 Show InChI InChI=1S/C26H21N3O3/c30-25(27-19-11-16-5-1-2-6-17(16)12-19)14-24-28-21-8-4-3-7-20(21)26(29-24)18-9-10-22-23(13-18)32-15-31-22/h1-10,13,19H,11-12,14-15H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25.1	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 20: 4561-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.014 BindingDB Entry DOI: 10.7270/Q2959JSG
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