Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 5' and Ligand = 'BDBM50304301' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50304301
(CHEMBL595790 | trans-N-[1-(3-Fluorophenyl)-1H-pyra...)Show SMILES Fc1ccc(cc1)-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(.68,-45.87,;.68,-44.33,;-.66,-43.55,;-.65,-42.02,;.68,-41.25,;2.01,-42.01,;2.02,-43.55,;.68,-39.72,;1.93,-38.81,;1.45,-37.35,;-.09,-37.35,;-.99,-36.1,;-2.53,-36.1,;-3.3,-34.77,;-3.31,-37.43,;-4.85,-37.43,;-5.62,-38.77,;-4.85,-40.09,;-3.31,-40.09,;-2.54,-38.77,;-3.93,-41.35,;-4.84,-42.61,;-4.36,-44.07,;-6.31,-42.13,;-7.65,-42.9,;-8.98,-42.13,;-8.98,-40.58,;-7.65,-39.81,;-6.31,-40.58,;-.56,-38.81,)| Show InChI InChI=1S/C22H19FN4O3/c23-15-1-3-16(4-2-15)27-12-8-19(26-27)25-20(28)14-5-9-22(10-6-14)18-13-24-11-7-17(18)21(29)30-22/h1-4,7-8,11-14H,5-6,9-10H2,(H,25,26,28)/t14-,22- | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from human recombinant Y5 receptor |
Bioorg Med Chem 17: 6971-82 (2009)
Article DOI: 10.1016/j.bmc.2009.08.019
BindingDB Entry DOI: 10.7270/Q2P26Z62 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Rat 6B) | BDBM50304301
(CHEMBL595790 | trans-N-[1-(3-Fluorophenyl)-1H-pyra...)Show SMILES Fc1ccc(cc1)-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1 |r,wU:17.21,wD:14.14,(.68,-45.87,;.68,-44.33,;-.66,-43.55,;-.65,-42.02,;.68,-41.25,;2.01,-42.01,;2.02,-43.55,;.68,-39.72,;1.93,-38.81,;1.45,-37.35,;-.09,-37.35,;-.99,-36.1,;-2.53,-36.1,;-3.3,-34.77,;-3.31,-37.43,;-4.85,-37.43,;-5.62,-38.77,;-4.85,-40.09,;-3.31,-40.09,;-2.54,-38.77,;-3.93,-41.35,;-4.84,-42.61,;-4.36,-44.07,;-6.31,-42.13,;-7.65,-42.9,;-8.98,-42.13,;-8.98,-40.58,;-7.65,-39.81,;-6.31,-40.58,;-.56,-38.81,)| Show InChI InChI=1S/C22H19FN4O3/c23-15-1-3-16(4-2-15)27-12-8-19(26-27)25-20(28)14-5-9-22(10-6-14)18-13-24-11-7-17(18)21(29)30-22/h1-4,7-8,11-14H,5-6,9-10H2,(H,25,26,28)/t14-,22- | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of rat Y5 receptor |
Bioorg Med Chem 17: 6971-82 (2009)
Article DOI: 10.1016/j.bmc.2009.08.019
BindingDB Entry DOI: 10.7270/Q2P26Z62 |
More data for this
Ligand-Target Pair | |
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