Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Neuropilin-1' and Ligand = 'BDBM50313491'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropilin-1 (Homo sapiens (Human))	BDBM50313491 ((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc2nsnc12)-[#6](-[#8])=O |r| Show InChI InChI=1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domainex Ltd Curated by ChEMBL					Assay Description Displacement of biotinylated-VEGF-A125 from NRP1 b1 domain by cell-free assay				J Med Chem 53: 2215-26 (2010) Article DOI: 10.1021/jm901755g BindingDB Entry DOI: 10.7270/Q2154H62
					More data for this Ligand-Target Pair
Neuropilin-1 (Homo sapiens (Human))	BDBM50313491 ((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc2nsnc12)-[#6](-[#8])=O |r| Show InChI InChI=1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domainex Ltd Curated by ChEMBL					Assay Description Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in human DU145 cells				J Med Chem 53: 2215-26 (2010) Article DOI: 10.1021/jm901755g BindingDB Entry DOI: 10.7270/Q2154H62
					More data for this Ligand-Target Pair
Neuropilin-1 (Homo sapiens (Human))	BDBM50313491 ((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc2nsnc12)-[#6](-[#8])=O |r| Show InChI InChI=1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domainex Ltd Curated by ChEMBL					Assay Description Displacement of [125I]VEGF-A from human NRP1 expressed in human A549 cells				J Med Chem 53: 2215-26 (2010) Article DOI: 10.1021/jm901755g BindingDB Entry DOI: 10.7270/Q2154H62
					More data for this Ligand-Target Pair
Neuropilin-1 (Homo sapiens (Human))	BDBM50313491 ((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc2nsnc12)-[#6](-[#8])=O |r| Show InChI InChI=1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domainex Ltd Curated by ChEMBL					Assay Description Displacement of [125I]VEGF-A from human NRP1 expressed in pig aortic endothelial cells				J Med Chem 53: 2215-26 (2010) Article DOI: 10.1021/jm901755g BindingDB Entry DOI: 10.7270/Q2154H62
					More data for this Ligand-Target Pair
Neuropilin-1 (Homo sapiens (Human))	BDBM50313491 ((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc2nsnc12)-[#6](-[#8])=O |r| Show InChI InChI=1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human biotinylated VEGF-165A expressed in HEK293 cells binding to immobilized recombinant full length human FC-tagged NRP1 ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115183 BindingDB Entry DOI: 10.7270/Q2GB27M4
					More data for this Ligand-Target Pair
Neuropilin-1 (Homo sapiens (Human))	BDBM50313491 ((S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-c1sccc1-[#7]S(=O)(=O)c1cccc2nsnc12)-[#6](-[#8])=O |r| Show InChI InChI=1S/C17H19N7O5S3/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Domainex Ltd Curated by ChEMBL					Assay Description Displacement of biotinylated-VEGF-A125 from human NRP1 expressed in HUVEC				J Med Chem 53: 2215-26 (2010) Article DOI: 10.1021/jm901755g BindingDB Entry DOI: 10.7270/Q2154H62
					More data for this Ligand-Target Pair