Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM50031217'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50031217 (CHEMBL262516 | N-((S)-1-{(S)-2-[(S)-1-(Benzooxazol...) Show SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)C(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nc2ccccc2o1 Show InChI InChI=1S/C34H42N4O7/c1-19(2)26(28(39)31-35-23-11-8-9-13-25(23)44-31)36-30(41)24-12-10-18-38(24)32(42)27(20(3)4)37-29(40)21-14-16-22(17-15-21)33(43)45-34(5,6)7/h8-9,11,13-17,19-20,24,26-27H,10,12,18H2,1-7H3,(H,36,41)(H,37,40)/t24-,26-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase				Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50031217 (CHEMBL262516 | N-((S)-1-{(S)-2-[(S)-1-(Benzooxazol...) Show SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)C(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nc2ccccc2o1 Show InChI InChI=1S/C34H42N4O7/c1-19(2)26(28(39)31-35-23-11-8-9-13-25(23)44-31)36-30(41)24-12-10-18-38(24)32(42)27(20(3)4)37-29(40)21-14-16-22(17-15-21)33(43)45-34(5,6)7/h8-9,11,13-17,19-20,24,26-27H,10,12,18H2,1-7H3,(H,36,41)(H,37,40)/t24-,26-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNa				J Med Chem 38: 3972-82 (1995) BindingDB Entry DOI: 10.7270/Q2T152NN
					More data for this Ligand-Target Pair