Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil elastase (Homo sapiens (Human)) | BDBM50291758 (5-Methyl-2-propylamino-benzo[d][1,3]oxazin-4-one |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Rate of deacylation by human leukocyte elastase | J Med Chem 30: 589-591 (1987) Article DOI: 10.1021/jm00387a001 BindingDB Entry DOI: 10.7270/Q2GQ6XRH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50291758 (5-Methyl-2-propylamino-benzo[d][1,3]oxazin-4-one |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.31 | n/a | n/a | n/a | n/a | 0.000339 | 5.62E+4 | n/a | n/a |
Syntex Research Curated by ChEMBL | Assay Description Component deacylation rate constant for interaction with human leukocyte elastase | J Med Chem 33: 464-79 (1990) Checked by Author BindingDB Entry DOI: 10.7270/Q2PR7X6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50291758 (5-Methyl-2-propylamino-benzo[d][1,3]oxazin-4-one |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | 0.000340 | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Rate of deacylation by human leukocyte elastase | J Med Chem 30: 589-591 (1987) Article DOI: 10.1021/jm00387a001 BindingDB Entry DOI: 10.7270/Q2GQ6XRH | |||||||||||
More data for this Ligand-Target Pair |