Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant for the inhibition of human Inducible nitric oxide synthase | Bioorg Med Chem Lett 7: 1763-1768 (1997) Article DOI: 10.1016/S0960-894X(97)00309-0 BindingDB Entry DOI: 10.7270/Q2TQ61J5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Mus musculus (mouse)) | BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University at Buffalo Curated by ChEMBL | Assay Description Compound was tested for competitive antagonist of Nitric oxide synthase | Bioorg Med Chem Lett 10: 1077-80 (2000) BindingDB Entry DOI: 10.7270/Q2959GSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Rattus norvegicus) | BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of rat brain inducible nitric oxide synthase | J Med Chem 37: 3886-8 (1994) BindingDB Entry DOI: 10.7270/Q29P328V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Mus musculus (mouse)) | BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Tested for inhibition of mouse inducible nitric oxide synthase | J Med Chem 37: 3886-8 (1994) BindingDB Entry DOI: 10.7270/Q29P328V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University Curated by ChEMBL | Assay Description Inhibitory concentration against human inducible nitric oxide synthase expressed in Sf-9 cells | Bioorg Med Chem Lett 15: 2881-5 (2005) Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Mus musculus (mouse)) | BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Haute-Alsace Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against iNOS obtained from RAW 264.7 cells. | Bioorg Med Chem Lett 8: 2961-6 (1999) Article DOI: 10.1016/S0960-894X(98)00532-0 BindingDB Entry DOI: 10.7270/Q2DZ07G5 | |||||||||||
More data for this Ligand-Target Pair |