Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM120133'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM120133 (US8697708, 22) Show SMILES Cc1cc(Nc2nccc3nc(sc23)-c2c(Cl)cc(CO)cc2Cl)ncn1 Show InChI InChI=1S/C18H13Cl2N5OS/c1-9-4-14(23-8-22-9)25-17-16-13(2-3-21-17)24-18(27-16)15-11(19)5-10(7-26)6-12(15)20/h2-6,8,26H,7H2,1H3,(H,21,22,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-50.9	n/a	n/a	n/a	n/a	n/a	7.2	22
F. Hoffmann-La Roche AG US Patent					Assay Description To determine the inhibition constants (Ki) of Examples 1-240, compounds were diluted serially in DMSO and added to 50 μL kinase reactions contai...				US Patent US8697708 (2014) BindingDB Entry DOI: 10.7270/Q2J38R6F
					More data for this Ligand-Target Pair