BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 5 group A member 2' and Ligand = 'BDBM22385'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nuclear receptor subfamily 5 group A member 2 (Homo sapiens (Human))	BDBM22385 ((3aS,6aR)-5-hexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	7.5	22
University of Southampton					Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv...				J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT
University of Southampton					More data for this Ligand-Target Pair
Nuclear receptor subfamily 5 group A member 2 (Homo sapiens (Human))	BDBM22385 ((3aS,6aR)-5-hexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexah...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31.6	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control				J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P
University of Southampton Curated by ChEMBL					More data for this Ligand-Target Pair