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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Opioid growth factor receptor-like protein 1' and Ligand = 'BDBM199339'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid growth factor receptor-like protein 1


(Homo sapiens (Human))
BDBM199339
PNG
(US9221831, 3)
Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(C=C)c5O[C@@H]2[C@]3(CCN1C)c45 |r,TLB:8:7:28.27:4.3|
Show InChI InChI=1S/C30H35NO3/c1-4-21-10-11-22-16-24-28-12-13-30(32-3,23(17-28)19-33-18-20-8-6-5-7-9-20)27-29(28,14-15-31(24)2)25(22)26(21)34-27/h4-11,23-24,27H,1,12-19H2,2-3H3/t23-,24-,27-,28-,29+,30-/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.07E+3 -35.2n/an/an/an/an/a7.450



Purdue Pharma, L.P.

US Patent


Assay Description
Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (Perkin Elmer, Shelton, Conn.; 87.7 Ci/mmole) with 12 ug mem...


US Patent US9221831 (2015)


BindingDB Entry DOI: 10.7270/Q2T72G8M
More data for this
Ligand-Target Pair
Opioid growth factor receptor-like protein 1


(Homo sapiens (Human))
BDBM199339
PNG
(US9221831, 3)
Show SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(C=C)c5O[C@@H]2[C@]3(CCN1C)c45 |r,TLB:8:7:28.27:4.3|
Show InChI InChI=1S/C30H35NO3/c1-4-21-10-11-22-16-24-28-12-13-30(32-3,23(17-28)19-33-18-20-8-6-5-7-9-20)27-29(28,14-15-31(24)2)25(22)26(21)34-27/h4-11,23-24,27H,1,12-19H2,2-3H3/t23-,24-,27-,28-,29+,30-/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 6.55E+3n/an/a7.450



Purdue Pharma, L.P.

US Patent


Assay Description
Functional [35S]GTPgammaS binding assays were conducted as follows. ORL-1 membrane solution was prepared by sequentially adding final concentrations ...


US Patent US9221831 (2015)


BindingDB Entry DOI: 10.7270/Q2T72G8M
More data for this
Ligand-Target Pair