Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM4203 (US8530494, 6 | US9221831, 10) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 532 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP US Patent | Assay Description Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... | US Patent US8530494 (2013) BindingDB Entry DOI: 10.7270/Q2JS9P3J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM4203 (US8530494, 6 | US9221831, 10) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 859 | -37.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (Perkin Elmer, Shelton, Conn.; 87.7 Ci/mmole) with 12 ug mem... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human)) | BDBM4203 (US8530494, 6 | US9221831, 10) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 1.64E+3 | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Functional [35S]GTPgammaS binding assays were conducted as follows. ORL-1 membrane solution was prepared by sequentially adding final concentrations ... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair |