Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM119639'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM119639 (US8680275, 196) Show SMILES FC(F)C(F)(F)Oc1ccccc1C(=O)N1CC[C@H]2CN([C@H]2C1)c1ccnc(n1)-c1ccccc1 |r| Show InChI InChI=1S/C25H22F4N4O2/c26-24(27)25(28,29)35-20-9-5-4-8-18(20)23(34)32-13-11-17-14-33(19(17)15-32)21-10-12-30-22(31-21)16-6-2-1-3-7-16/h1-10,12,17,19,24H,11,13-15H2/t17-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14	-41.7	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
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