Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM119666'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119666 (US8680275, 38) Show SMILES CN(C)c1nc(cc(n1)C(F)(F)F)N1CC2CCN(CC12)C(=O)c1ccc(F)cc1-n1nccn1 Show InChI InChI=1S/C22H22F4N8O/c1-31(2)21-29-18(22(24,25)26)10-19(30-21)33-11-13-5-8-32(12-17(13)33)20(35)15-4-3-14(23)9-16(15)34-27-6-7-28-34/h3-4,6-7,9-10,13,17H,5,8,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16	-41.4	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
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