Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxidized low-density lipoprotein receptor 1' and Ligand = 'BDBM454336'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxidized low-density lipoprotein receptor 1 (Bovine)	BDBM454336 (US10717734, Compound 12) Show SMILES Cc1c(Cc2ccc(cc2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN Show InChI InChI=1S/C21H24FN3O2S/c1-14-4-9-20-21(24-14)19(15(2)25(20)13-17(22)10-11-23)12-16-5-7-18(8-6-16)28(3,26)27/h4-10H,11-13,23H2,1-3H3/b17-10-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
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