Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM20170'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM20170 (2-(3-{3-[(2,2-diphenylethyl)[(2-fluoro-4-methoxyph...) Show SMILES COc1ccc(CN(CCCOc2cccc(CC(N)=O)c2)CC(c2ccccc2)c2ccccc2)c(F)c1 Show InChI InChI=1S/C33H35FN2O3/c1-38-29-17-16-28(32(34)22-29)23-36(18-9-19-39-30-15-8-10-25(20-30)21-33(35)37)24-31(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-8,10-17,20,22,31H,9,18-19,21,23-24H2,1H3,(H2,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G
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