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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM50252905'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM50252905
PNG
(2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)
Show SMILES CCCCN(Cc1cc(OC(F)(F)F)ccc1O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C21H20F9NO3/c1-2-3-10-31(12-13-11-16(8-9-17(13)32)34-21(28,29)30)15-6-4-14(5-7-15)18(33,19(22,23)24)20(25,26)27/h4-9,11,32-33H,2-3,10,12H2,1H3
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Article
PubMed
n/an/a 190n/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRalpha ligand binding domain

J Med Chem 51: 5758-65 (2008)


Article DOI: 10.1021/jm800612u
BindingDB Entry DOI: 10.7270/Q28052FN
More data for this
Ligand-Target Pair