Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-beta' and Ligand = 'BDBM304378'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM304378 ((R)-4-fluoro-2-(4-(4-fluoro-3-(methylsulfonyl)phen...) Show SMILES CC(C)[C@@H]1CN(CCN1c1nc2c(F)cccc2s1)c1ccc(F)c(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C21H23F2N3O2S2/c1-13(2)17-12-25(14-7-8-15(22)19(11-14)30(3,27)28)9-10-26(17)21-24-20-16(23)5-4-6-18(20)29-21/h4-8,11,13,17H,9-10,12H2,1-3H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair