BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P2Y purinoceptor 14' and Ligand = 'BDBM50343093'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 14


(Mus musculus)		BDBM50343093
PNG
(2-(3-cyanophenyl)-N-(3-ethylphenyl)-4-o-tolyl-7,8-...)
Show SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2C)-c2cccc(c2)C#N)c1
Show InChI InChI=1S/C30H27N5O/c1-3-21-9-7-12-24(17-21)32-30(36)35-15-14-27-26(19-35)28(25-13-5-4-8-20(25)2)34-29(33-27)23-11-6-10-22(16-23)18-31/h4-13,16-17H,3,14-15,19H2,1-2H3,(H,32,36)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Merck Frosst Center for Therapeutic Research

Curated by ChEMBL


Assay Description
Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...

Bioorg Med Chem Lett 21: 2832-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.084
BindingDB Entry DOI: 10.7270/Q20865N7
More data for this
Ligand-Target Pair