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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P2Y purinoceptor 14' and Ligand = 'BDBM50343111'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 14


(Mus musculus)		BDBM50343111
PNG
(CHEMBL1771246 | N-(3-chloro-5-ethylphenyl)-2-(pyri...)
Show SMILES CCc1cc(Cl)cc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2C)-c2cccnc2)c1
Show InChI InChI=1S/C28H26ClN5O/c1-3-19-13-21(29)15-22(14-19)31-28(35)34-12-10-25-24(17-34)26(23-9-5-4-7-18(23)2)33-27(32-25)20-8-6-11-30-16-20/h4-9,11,13-16H,3,10,12,17H2,1-2H3,(H,31,35)
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PubMed
n/an/a 160n/an/an/an/an/an/a



Merck Frosst Center for Therapeutic Research

Curated by ChEMBL


Assay Description
Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...

Bioorg Med Chem Lett 21: 2832-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.084
BindingDB Entry DOI: 10.7270/Q20865N7
More data for this
Ligand-Target Pair