Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 2' and Ligand = 'BDBM350835'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POU domain, class 2, transcription factor 2 (Homo sapiens (Human))	BDBM350835 (US9795602, Compound 25b) Show SMILES [H][C@]12CCO[C@@]1([H])N(CC)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)c(Cl)c1F |r| Show InChI InChI=1S/C20H18ClF2N3O5/c1-2-25-19(30)15-17(28)16(27)10(8-26(15)12-5-6-31-20(12)25)18(29)24-7-9-3-4-11(22)13(21)14(9)23/h3-4,8,12,20,28H,2,5-7H2,1H3,(H,24,29)/t12-,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...				US Patent US9795602 (2017) BindingDB Entry DOI: 10.7270/Q2K35WTB
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