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Found 1 hit Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 2' and Ligand = 'BDBM448216'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
POU domain, class 2, transcription factor 2


(Homo sapiens (Human))		BDBM448216
PNG
(US10689399, Compound 100)
Show SMILES Fc1ccc(F)c(CNC(=O)c2cn3CC4C5CCC(C5)N4C(=O)c3cc2=O)c1 |THB:14:15:18.17:20,22:21:18.17:20|
Show InChI InChI=1S/C21H19F2N3O3/c22-13-2-4-16(23)12(5-13)8-24-20(28)15-9-25-10-18-11-1-3-14(6-11)26(18)21(29)17(25)7-19(15)27/h2,4-5,7,9,11,14,18H,1,3,6,8,10H2,(H,24,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 450n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...

US Patent US10689399 (2020)


BindingDB Entry DOI: 10.7270/Q2S185HX
More data for this
Ligand-Target Pair