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Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptide deformylase, mitochondrial' and Ligand = 'BDBM50542157'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptide deformylase, mitochondrial


(Homo sapiens (Human))		BDBM50542157
PNG
(CHEMBL4646467)
Show SMILES CCc1ccc(cc1)-c1noc(n1)[C@@H]1CC2(CC2)CN1C(=O)[C@H](CC1CCCC1)CC(=O)NO |r|
Show InChI InChI=1S/C26H34N4O4/c1-2-17-7-9-19(10-8-17)23-27-24(34-29-23)21-15-26(11-12-26)16-30(21)25(32)20(14-22(31)28-33)13-18-5-3-4-6-18/h7-10,18,20-21,33H,2-6,11-16H2,1H3,(H,28,31)/t20-,21+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.80n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human PDF expressed in Escherichia coli BL21 pLysS using formyl-Met-Ala-His-Ala peptide as substrate measured after 1 hr by fluorescami...

J Med Chem 63: 6959-6978 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00079
BindingDB Entry DOI: 10.7270/Q2125X6C
More data for this
Ligand-Target Pair