BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor gamma' and Ligand = 'BDBM28756'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28756 (2-methyl-2-[2-methyl-4-({3-[4-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma-Gal4 in HEK293 cells by luciferase reporter assay				Bioorg Med Chem 16: 3321-41 (2008) Article DOI: 10.1016/j.bmc.2007.12.005 BindingDB Entry DOI: 10.7270/Q28W3F5T
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28756 (2-methyl-2-[2-methyl-4-({3-[4-(trifluoromethyl)phe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...				J Med Chem 50: 3954-63 (2007) Article DOI: 10.1021/jm070511x BindingDB Entry DOI: 10.7270/Q2H41PR5
Johnson & Johnson Pharmaceutical					More data for this Ligand-Target Pair