Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50122347 ((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
TBA | Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge... | Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50122347 ((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
TBA | Assay Description Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge... | Citation and Details Article DOI: 10.1007/s00044-012-0003-4 BindingDB Entry DOI: 10.7270/Q280544F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50122347 ((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | 891 | n/a | n/a | n/a | n/a |
TBA | Assay Description Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay | Citation and Details Article DOI: 10.1007/s00044-011-9818-7 BindingDB Entry DOI: 10.7270/Q2R49TNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50122347 ((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 590 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S Curated by ChEMBL | Assay Description Activity at human adipose tissue PPAR gamma expressed in HEK293 cells by PPAR-GAL4 transactivation assay | J Med Chem 50: 1495-503 (2007) Article DOI: 10.1021/jm061202u BindingDB Entry DOI: 10.7270/Q2J9662B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50122347 ((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
The University of Tokyo Curated by ChEMBL | Assay Description Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15. | Bioorg Med Chem Lett 27: 3131-3134 (2017) Article DOI: 10.1016/j.bmcl.2017.05.037 BindingDB Entry DOI: 10.7270/Q20867QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50122347 ((S)-3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-pheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S Curated by ChEMBL | Assay Description In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma) | Bioorg Med Chem Lett 13: 257-60 (2002) BindingDB Entry DOI: 10.7270/Q2FF3RQS | |||||||||||
More data for this Ligand-Target Pair |