BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor gamma' and Ligand = 'BDBM50179249'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179249 (2-ethyl-2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179249 (2-ethyl-2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Functional activity at human PPAR gamma in Huh7 cells by transactivation assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair