Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM109316'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM109316 (US8609666, 36) Show SMILES COCCNc1cc(nc2c(nc(nc12)N1CCOCC1)-c1cccc(F)c1O)C(O)=O Show InChI InChI=1S/C21H22FN5O5/c1-31-8-5-23-14-11-15(20(29)30)24-18-16(12-3-2-4-13(22)19(12)28)25-21(26-17(14)18)27-6-9-32-10-7-27/h2-4,11,28H,5-10H2,1H3,(H,23,24)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono SA US Patent					Assay Description The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...				US Patent US8609666 (2013) BindingDB Entry DOI: 10.7270/Q26M35G5
					More data for this Ligand-Target Pair