Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM151000'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM151000 (US8987257, 13) Show SMILES C[C@H]1COCCN1c1nc(nc2[nH]c(nc12)-c1cnc2cc[nH]c2c1)N1CCOCC1 |r| Show InChI InChI=1S/C21H22N8O2/c1-13-12-31-9-6-29(13)20-17-19(26-21(27-20)28-4-7-30-8-5-28)25-18(24-17)14-10-16-15(23-11-14)2-3-22-16/h2-3,10-11,13H,4-9,12H2,1H3/b18-14+/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description PI3K KinaseGlo assay: 50 mL of compound dilutions were dispensed onto black 384-well low volume Non Binding Styrene (NBS) plates (Costar Cat. No. NBS...				US Patent US8987257 (2015) BindingDB Entry DOI: 10.7270/Q2S75F2B
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