Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM172654'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172654 (US9090628, 314 | US9090628, 318 | US9090628, 320) Show SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC11CCCN(C)C1 Show InChI InChI=1S/C26H35N7O/c1-18(2)33-25(27-19(3)29-33)22-16-31-13-14-34-23-15-20(7-8-21(23)24(31)28-22)32-12-6-10-26(32)9-5-11-30(4)17-26/h7-8,15-16,18H,5-6,9-14,17H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.178	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172654 (US9090628, 314 | US9090628, 318 | US9090628, 320) Show SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC11CCCN(C)C1 Show InChI InChI=1S/C26H35N7O/c1-18(2)33-25(27-19(3)29-33)22-16-31-13-14-34-23-15-20(7-8-21(23)24(31)28-22)32-12-6-10-26(32)9-5-11-30(4)17-26/h7-8,15-16,18H,5-6,9-14,17H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.236	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172654 (US9090628, 314 | US9090628, 318 | US9090628, 320) Show SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC11CCCN(C)C1 Show InChI InChI=1S/C26H35N7O/c1-18(2)33-25(27-19(3)29-33)22-16-31-13-14-34-23-15-20(7-8-21(23)24(31)28-22)32-12-6-10-26(32)9-5-11-30(4)17-26/h7-8,15-16,18H,5-6,9-14,17H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.335	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair