Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM464392'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM464392 (US10792283, Compound 2) Show SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1cc2ccc(F)cc2nc1-c1ccccn1 Show InChI InChI=1S/C21H17FN8/c1-11(27-20-15(10-23)19(24)29-21(25)30-20)14-8-12-5-6-13(22)9-17(12)28-18(14)16-4-2-3-7-26-16/h2-9,11H,1H3,(H5,24,25,27,29,30)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0860	n/a	n/a	n/a	n/a	n/a	n/a
HANGZHOU ZHENGXIANG PHARMACEUTICALS CO., LTD. US Patent					Assay Description Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...				US Patent US10792283 (2020) BindingDB Entry DOI: 10.7270/Q2ZK5KQH
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