Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM342556'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM342556 (US10329299, Compound 107 | US10675286, Compound 10...) Show SMILES Cn1cc(cn1)C#Cc1cccc2cc(CNC(=O)c3c(N)nn4cccnc34)n(-c3ccccc3)c(=O)c12 |$;;;;;;;;;;;;;;;;;;;;;N;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C29H22N8O2/c1-35-18-19(16-33-35)11-12-20-7-5-8-21-15-23(37(29(39)24(20)21)22-9-3-2-4-10-22)17-32-28(38)25-26(30)34-36-14-6-13-31-27(25)36/h2-10,13-16,18H,17H2,1H3,(H2,30,34)(H,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Infinity Pharmaceuticals, Inc. US Patent					Assay Description Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or ...				US Patent US9775844 (2017) BindingDB Entry DOI: 10.7270/Q2GQ70WH
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM342556 (US10329299, Compound 107 | US10675286, Compound 10...) Show SMILES Cn1cc(cn1)C#Cc1cccc2cc(CNC(=O)c3c(N)nn4cccnc34)n(-c3ccccc3)c(=O)c12 |$;;;;;;;;;;;;;;;;;;;;;N;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C29H22N8O2/c1-35-18-19(16-33-35)11-12-20-7-5-8-21-15-23(37(29(39)24(20)21)22-9-3-2-4-10-22)17-32-28(38)25-26(30)34-36-14-6-13-31-27(25)36/h2-10,13-16,18H,17H2,1H3,(H2,30,34)(H,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description A PI3-Kinase HTRF® assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used spec...				Bioorg Med Chem 17: 6567-82 (2009) BindingDB Entry DOI: 10.7270/Q2KK9F5S
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM342556 (US10329299, Compound 107 | US10675286, Compound 10...) Show SMILES Cn1cc(cn1)C#Cc1cccc2cc(CNC(=O)c3c(N)nn4cccnc34)n(-c3ccccc3)c(=O)c12 |$;;;;;;;;;;;;;;;;;;;;;N;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C29H22N8O2/c1-35-18-19(16-33-35)11-12-20-7-5-8-21-15-23(37(29(39)24(20)21)22-9-3-2-4-10-22)17-32-28(38)25-26(30)34-36-14-6-13-31-27(25)36/h2-10,13-16,18H,17H2,1H3,(H2,30,34)(H,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Infinity Pharmaceuticals, Inc. US Patent					Assay Description A PI3-Kinase HTRF® assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used spec...				US Patent US10675286 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G4R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM342556 (US10329299, Compound 107 | US10675286, Compound 10...) Show SMILES Cn1cc(cn1)C#Cc1cccc2cc(CNC(=O)c3c(N)nn4cccnc34)n(-c3ccccc3)c(=O)c12 |$;;;;;;;;;;;;;;;;;;;;;N;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C29H22N8O2/c1-35-18-19(16-33-35)11-12-20-7-5-8-21-15-23(37(29(39)24(20)21)22-9-3-2-4-10-22)17-32-28(38)25-26(30)34-36-14-6-13-31-27(25)36/h2-10,13-16,18H,17H2,1H3,(H2,30,34)(H,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description PI3 Kinase α, β, γ or δ activity was assayed using the PI3 Kinase HTRF® assay kit (catalogue No. 33-016) purchased from Millipore...				Citation and Details BindingDB Entry DOI: 10.7270/Q25T3QBR
					More data for this Ligand-Target Pair