Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase' and Ligand = 'BDBM153397'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Trypanosoma brucei)	BDBM153397 (6-(3-(1H-Tetrazol-5-yl)phenyl)-4-((3-methoxyphenyl...) Show SMILES COc1cccc(Nc2c(cnc3c(C)cc(cc23)-c2cccc(c2)-c2nnn[nH]2)C(N)=O)c1 Show InChI InChI=1S/C25H21N7O2/c1-14-9-17(15-5-3-6-16(10-15)25-29-31-32-30-25)11-20-22(14)27-13-21(24(26)33)23(20)28-18-7-4-8-19(12-18)34-2/h3-13H,1-2H3,(H2,26,33)(H,27,28)(H,29,30,31,32)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	7.4	n/a
Northeastern University					Assay Description In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25µM cAMP (Enzo Lifesci...				Chem Biol Drug Des 85: 549-64 (2015) Article DOI: 10.1111/cbdd.12443 BindingDB Entry DOI: 10.7270/Q2FF3R28
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