Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phospholipase D' and Ligand = 'BDBM123751'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (Streptomyces sp. PMF)	BDBM123751 (1-(2-ethylphenyl)-3-(naphthalen-2-yl)-1H-pyrazolo[...) Show SMILES CCc1ccccc1-n1nc(-c2ccc3ccccc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H19N5/c1-2-15-7-5-6-10-19(15)28-23-20(22(24)25-14-26-23)21(27-28)18-12-11-16-8-3-4-9-17(16)13-18/h3-14H,2H2,1H3,(H2,24,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	355	n/a	n/a	n/a	n/a	n/a	37
University of Massachusetts Boston					Assay Description PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...				Chem Biol Drug Des 84: 270-81 (2014) Article DOI: 10.1111/cbdd.12319 BindingDB Entry DOI: 10.7270/Q2HT2N05
					More data for this Ligand-Target Pair
Phospholipase D (Streptomyces chromofuscus)	BDBM123751 (1-(2-ethylphenyl)-3-(naphthalen-2-yl)-1H-pyrazolo[...) Show SMILES CCc1ccccc1-n1nc(-c2ccc3ccccc3c2)c2c(N)ncnc12 Show InChI InChI=1S/C23H19N5/c1-2-15-7-5-6-10-19(15)28-23-20(22(24)25-14-26-23)21(27-28)18-12-11-16-8-3-4-9-17(16)13-18/h3-14H,2H2,1H3,(H2,24,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	8.0	n/a
Roxbury Community College					Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...				Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V
					More data for this Ligand-Target Pair