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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-activating factor acetylhydrolase' and Ligand = 'BDBM50107484'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-activating factor acetylhydrolase


(Homo sapiens (Human))
BDBM50107484
PNG
(CHEMBL150823 | N-Biphenyl-4-ylmethyl-4-[2-(4-fluor...)
Show SMILES Cn1cc(Cc2cn(CCCC(=O)NCc3ccc(cc3)-c3ccccc3)c(SCc3ccc(F)cc3)nc2=O)cn1
Show InChI InChI=1S/C33H32FN5O2S/c1-38-21-26(20-36-38)18-29-22-39(33(37-32(29)41)42-23-25-11-15-30(34)16-12-25)17-5-8-31(40)35-19-24-9-13-28(14-10-24)27-6-3-2-4-7-27/h2-4,6-7,9-16,20-22H,5,8,17-19,23H2,1H3,(H,35,40)
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PubMed
n/an/a 5n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).


Bioorg Med Chem Lett 12: 51-5 (2001)


BindingDB Entry DOI: 10.7270/Q2862FR5
More data for this
Ligand-Target Pair