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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta' and Ligand = 'BDBM50118869'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor alpha/beta


(Homo sapiens (Human))		BDBM50118869
PNG
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Show SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)NCc3ccc(cc3)C(C)(C)C)c2cc1OC
Show InChI InChI=1S/C26H33N5O3/c1-26(2,3)19-8-6-18(7-9-19)16-27-25(32)31-12-10-30(11-13-31)24-20-14-22(33-4)23(34-5)15-21(20)28-17-29-24/h6-9,14-15,17H,10-13,16H2,1-5H3,(H,27,32)
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Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...

J Med Chem 45: 4513-23 (2002)


BindingDB Entry DOI: 10.7270/Q2JH3MXF
More data for this
Ligand-Target Pair