Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM139617'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM139617 (US8889870, 165 | US9388176, 165 | US9820989, 165) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)N2CCc3ccncc3C2)cc1 Show InChI InChI=1S/C22H22N4O/c1-16-2-4-19(5-3-16)24-22(27)25-20-6-8-21(9-7-20)26-13-11-17-10-12-23-14-18(17)15-26/h2-10,12,14H,11,13,15H2,1H3,(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM139617 (US8889870, 165 | US9388176, 165 | US9820989, 165) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)N2CCc3ccncc3C2)cc1 Show InChI InChI=1S/C22H22N4O/c1-16-2-4-19(5-3-16)24-22(27)25-20-6-8-21(9-7-20)26-13-11-17-10-12-23-14-18(17)15-26/h2-10,12,14H,11,13,15H2,1H3,(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc. US Patent					Assay Description Biochemical PDGFR.beta. kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 .mu.g of poly-Glu-Tyr (4:1) in 1...				US Patent US8889870 (2014) BindingDB Entry DOI: 10.7270/Q25B0158
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM139617 (US8889870, 165 | US9388176, 165 | US9820989, 165) Show SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)N2CCc3ccncc3C2)cc1 Show InChI InChI=1S/C22H22N4O/c1-16-2-4-19(5-3-16)24-22(27)25-20-6-8-21(9-7-20)26-13-11-17-10-12-23-14-18(17)15-26/h2-10,12,14H,11,13,15H2,1H3,(H2,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in 1...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair