Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM445218'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445218 (US10669235, Example 9 | US11208381, Example 9) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN3CCNC(=O)C3)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H31N5O5/c1-19-16-24-25(17-23(19)31(40)41-2)35-30(39)27(24)28(20-6-4-3-5-7-20)34-22-10-8-21(9-11-22)29(38)33-13-15-36-14-12-32-26(37)18-36/h3-11,16-17,34H,12-15,18H2,1-2H3,(H,32,37)(H,33,38)(H,35,39)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445218 (US10669235, Example 9 | US11208381, Example 9) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN3CCNC(=O)C3)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H31N5O5/c1-19-16-24-25(17-23(19)31(40)41-2)35-30(39)27(24)28(20-6-4-3-5-7-20)34-22-10-8-21(9-11-22)29(38)33-13-15-36-14-12-32-26(37)18-36/h3-11,16-17,34H,12-15,18H2,1-2H3,(H,32,37)(H,33,38)(H,35,39)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair