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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50181317'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50181317
PNG
(3-(1H-benzo[d]imidazol-2-yl)-4-hydroxyquinolin-2(1...)
Show SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12
Show InChI InChI=1S/C16H11N3O2/c20-14-9-5-1-2-6-10(9)19-16(21)13(14)15-17-11-7-3-4-8-12(11)18-15/h1-8H,(H,17,18)(H2,19,20,21)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDGFRbeta


J Med Chem 52: 278-92 (2009)


Article DOI: 10.1021/jm800790t
BindingDB Entry DOI: 10.7270/Q2TD9X7X
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Mus musculus (mouse))
BDBM50181317
PNG
(3-(1H-benzo[d]imidazol-2-yl)-4-hydroxyquinolin-2(1...)
Show SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12
Show InChI InChI=1S/C16H11N3O2/c20-14-9-5-1-2-6-10(9)19-16(21)13(14)15-17-11-7-3-4-8-12(11)18-15/h1-8H,(H,17,18)(H2,19,20,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 395n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against PDGFRbeta


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair