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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50437508'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50437508
PNG
(CHEMBL2409779)
Show SMILES Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n(C)n1
Show InChI InChI=1S/C23H22N6O3/c1-14-10-19(28(2)27-14)23(31)24-16-4-3-5-17(11-16)32-18-8-9-21-25-20(13-29(21)12-18)26-22(30)15-6-7-15/h3-5,8-13,15H,6-7H2,1-2H3,(H,24,31)(H,26,30)
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PC cid
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Article
PubMed
n/an/a 5.90n/an/an/an/an/an/a



Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...

Bioorg Med Chem 21: 4714-29 (2013)


Article DOI: 10.1016/j.bmc.2013.04.042
BindingDB Entry DOI: 10.7270/Q2ZS2XZQ
More data for this
Ligand-Target Pair