Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27670'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27670 (2-{2-[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]et...) Show SMILES NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C20H22FN3O3/c21-17-6-5-14(13-16(17)20(26)24-10-8-23-9-11-24)7-12-27-18-4-2-1-3-15(18)19(22)25/h1-6,13,23H,7-12H2,(H2,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
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